U.S. Smokers Face a Maze of Conflicting Nicotine Risk Messages
Doctors Must Explain How Switching From Cigarettes May Lower Health Risks
Our Mission
We connect researchers from across the University of Pennsylvania with a common mission: to improve health and health care by catalyzing collaborative, multidisciplinary research that influences policy and practice.
Featured Research Updates
LDI generates critical evidence to improve U.S. health care delivery, patient care, and health policy.
Addiction Consults Improve Substance Use Care Without More Readmissions or Longer Stays
LDI Fellows’ Study Backs Hospital Addiction Care Model, Although Financial Gains Remain Unproven
Heat-Related Deaths May Be Far Higher Than Reported
Chart of the Day: U.S. Misses Heat Deaths That Occur Outside Work, LDI Fellows Say
Penn’s Mark Pauly Calls on States to Revive Hospital Competition to Control Costs
New Study Finds Many Local Markets Could Support More Competing Hospitals
Reaching Across the Aisle to Lower Health Care Costs
Two Health Policy Experts Find Bipartisan Consensus in Site Neutral Payments, Controlling Medicare Costs
Military Surgeons Saw More Readmissions After Returning From Deployment
Leaves May Decay Doctors’ Skills, so Hospitals Need a Plan for Reentry, LDI Expert Says
Upcoming Events
In-Person Event
2026 J. Sanford “Sandy” Schwartz Memorial Grand Rounds with Peter Ubel, MD
Are Medical Experts Asking Patient Preferences to do Their Dirty Work?
Open to Penn Affiliates
In-Person Event
Practicing Where It Matters Most: The Future of Community-Based Primary Care
Inaugural Leonard A. Lauder Community Care Nurse Practitioner Program Symposium
Our Experts
Our 500+ Fellows are national experts and thought leaders who bridge all of Penn’s schools, the University of Pennsylvania Health System, and the Children’s Hospital of Philadelphia.
Marilyn Schapira, MD, MPH
- Professor, General Internal Medicine , Perelman School of Medicine
Connie Ulrich, PhD, RN
- Professor, Biobehavioral Health Sciences , Penn Nursing
- Professor, Medical Ethics and Health Policy , Perelman School of Medicine
Alex Rees-Jones, PhD
- Associate Professor, Business Economics and Public Policy , Wharton School
Mucio Kit Delgado, MD, MS
- Associate Professor, Emergency Medicine , Perelman School of Medicine
- Associate Professor, Addiction Medicine , Perelman School of Medicine
Marina Serper, MD, MS
- Associate Professor, Medicine , Perelman School of Medicine
Arnold Rosoff, JD
- Professor Emeritus, Legal Studies and Business Ethics , Wharton School
Lee Fleisher, MD
- Emeritus Professor, Anesthesiology and Critical Care , Perelman School of Medicine
- Former Chief Medical Officer and Director, Center for Clinical Standards and Quality, Centers for Medicare and Medicaid Services (2020-2023)
Taras Grosh, MD
- Assistant Professor, Anesthesiology and Critical Care , Perelman School of Medicine
What We Do
As Penn’s hub for health care delivery, health policy, and population health, we connect and amplify over 500 Fellows across the University, and train the next generation of researchers.
Fast Facts
$179M+
Awarded in External Grant Funding
12,100+
Journal Articles Published (2021–2025)
$622K+
Awarded in Research Grants from LDI
Our Impact
Penn LDI’s success stems from creating multidisciplinary solutions to our nation’s most pressing health care problems. Explore 20 stories about the transformative power of our institute.
